Cast lineup, character roles, and changes from previous seasons Series: Prison Break (Fox, 2005–2009) Season: 3 (Premiered September 17, 2007; concluded February 18, 2008) Setting: Sona Federal Prison, Panama (following the season 2 finale) 1. Overview Season 3 of Prison Break underwent significant cast restructuring due to storyline shifts, budget considerations, and character departures. The setting moved from U.S. penitentiaries to the violent, lawless Sona prison in Panama. The core ensemble remained, but several major characters from seasons 1–2 were either absent or had reduced roles. 2. Main Cast (Starring) The following actors were listed as series regulars during Season 3:
Prison Break Cast: Season 3 Site
Cast lineup, character roles, and changes from previous seasons Series: Prison Break (Fox, 2005–2009) Season: 3 (Premiered September 17, 2007; concluded February 18, 2008) Setting: Sona Federal Prison, Panama (following the season 2 finale) 1. Overview Season 3 of Prison Break underwent significant cast restructuring due to storyline shifts, budget considerations, and character departures. The setting moved from U.S. penitentiaries to the violent, lawless Sona prison in Panama. The core ensemble remained, but several major characters from seasons 1–2 were either absent or had reduced roles. 2. Main Cast (Starring) The following actors were listed as series regulars during Season 3:
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